Moisturizing Cream for Face & Body
Dr. Eddie’s Dermal Defense Moisturizing Cream provides daily hydration for dry, sensitive and eczema-prone skin. Glycerin draws moisture into the outer skin, while petrolatum helps reduce water loss. Use the same fragrance-free cream on your face, hands and body.
Ingredients We Use
A fragrance-free cream with glycerin for hydration and petrolatum to help keep that moisture in your skin. Explore the cream’s ingredients.
Fragrance-Free
Made without added fragrance or masking fragrance.
Daily Moisture
Glycerin and petrolatum help dry skin stay hydrated.
Face & Body
One leave-on cream for dry facial skin, hands, arms and legs.
Pediatrician-Developed
Created by Dr. Eddie Valenzuela, a board-certified pediatrician.
About Dermal Defense
Dermal Defense was created by Dr. Eddie Valenzuela, MD, FAAP, a board-certified pediatrician and founder of Pediatric Solutions, LLC. His work caring for families inspired a straightforward approach to dry, sensitive skin: useful ingredients and a routine people can follow.
Our Moisturizing Cream is a leave-on moisturizer for the face and body. It supports daily skin hydration and fits alongside gentle cleansing and any treatment your clinician recommends.
Our Latest Stories

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Using Dermal Defense Cream on the Face and Body
Apply Dermal Defense Moisturizing Cream to dry face and body skin, including beneath facial hair, with practical guidance on timing and skin comfort.
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Choosing a Fragrance-Free Cleanser for Eczema-Prone Skin
Choose a cleanser for eczema-prone skin by checking fragrance, rinsing, skin comfort and how cleansing fits with moisturizing.
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Botanical Ingredients in Eczema Skin Care: Evidence and Limits
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Dermal Defense Cream and Skin-Barrier Moisture Support
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Eczema on Black Skin: Daily Care and Lasting Color Changes
Care for eczema-prone Black skin, distinguish ongoing inflammation from lingering color changes, and avoid irritating attempts to fade marks.
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A Daily Skin-Care Routine for Eczema-Prone Skin
Build a practical eczema skin-care routine with gentle cleansing, regular moisturizing, trigger awareness and prescribed treatment when needed.
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Read MoreUsing Dermal Defense Cream
Make moisturizing a comfortable part of your daily routine.
Daily application on face and body
Apply the cream to clean skin on your face and body twice daily or as needed. After washing, pat gently and moisturize while the skin is still slightly damp. Work a small amount through facial hair to reach dry skin beneath it.
Using cream alongside other skin care
Use the cream after a gentle cleanser. If you use a prescribed skin treatment, follow your clinician’s directions for when to apply it. The cream provides moisture support; it is not a medicated eczema or dandruff treatment.
Ingredients that support moisture
Glycerin attracts moisture, and petrolatum helps limit water loss from the skin’s surface. The fragrance-free formula also includes a licorice-derived ingredient, dipotassium glycyrrhizate. See the full ingredient list.
Choosing for sensitive skin
Check the full ingredient list if you have a known allergy. For an infant, a persistent rash or a history of product reactions, ask your clinician which moisturizer is appropriate.
Customer Experiences

Charlotte Moore
“I bought dermal defense for my son who has very sensitive skin and it’s been such a relief. It’s not only helped with his skin condition but he loves how soft and comfortable his skin feels now. I feel better knowing i’m using a product thats gentle and safe.”

Liam Wilson
“As someone who’s tried countless skincare products, i was pleasantly surprised by how gentle yet effective dermal defense is. My skin feels smoother and less inflamed and it doesn’t leave any greasy residue. It’s the first product i’ve used that actually addresses my sensitive skin without any burning sensation.”

Ava Martinez
“Finally! A product that lives up to the hype. Dermal defense cleared up the irritation on my face after just a couple of uses. My skin feels soft and looks healthier than it has in months. I’m pretty much hooked!”
Customer Experiences
Read experiences shared by Dermal Defense customers, then explore the cream ingredients and application guidance to see how moisturizing fits your routine.
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Customer Experiences
Read experiences shared by Dermal Defense customers, then explore the cream ingredients and application guidance to see how moisturizing fits your routine.
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